These medications reduce neurotransmission and might help some forms of dystonia. Diazepam (Valium, Diastat, others), clonazepam (Klonopin) and baclofen (Lioresal, Gablofen, others).
Side effects can include sedation, nervousness, depression or insomnia. Side effects can include memory loss, blurred vision, drowsiness, dry mouth and constipation. These two medications act on neurotransmitters other than dopamine. This drug may also be used as a trial to help diagnose certain types of dystonia. This medication can increase levels of the neurotransmitter dopamine.
Other medications target chemicals in your brain (neurotransmitters) that affect muscle movement. They can include weakness, dry mouth or voice changes. Side effects are generally mild and temporary. Injections are usually repeated every 3 to 4 months. Injections of botulinum toxin (Botox, Dysport, others) into specific muscles might reduce or stop your muscle spasms. To manage dystonia, your provider might recommend a combination of medications, therapy or surgery.
